Inhaled Technosphere Insulin in Children with Diabetes: The INHALE-1 Extension Study

The INHALE-1 extension phase showed no safety concerns. Although HbA1c levels deteriorated slightly during the study, in view of the safety profile and increased patient satisfaction in the RCT portion of the trial, TI may be a useful treatment option for some pediatric patients with diabetes, particularly for those who choose not to or are unable to use an AID system.

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Publication Details

Journal
Diabetes Technology & Therapeutics
Published
2026-02-04
DOI
https://doi.org/10.1177/15209156261420176
Primary Topic
Inhalation and Respiratory Drug Delivery
Type
article
Field-Weighted Citation Impact
0.00
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article

Inhaled Technosphere Insulin in Children with Diabetes: The INHALE-1 Extension Study

Patrick C. Hanley, KRISTINA COSSEN, Joanna Kramer, Jamie Wood et al.
Diabetes Technology & Therapeutics
Inhalation and Respiratory Drug Delivery
article

Inhaled Technosphere Insulin in Children with Diabetes: The INHALE-1 Extension Study

Patrick C. Hanley, KRISTINA COSSEN, Joanna Kramer, Jamie Wood, Steven M. Willi, Lauren Kanapka, for the INHALE-1 Study Group, Michael Tansey, Perrin C. White, Kathleen E. Bethin, Roy W. Beck, Anna Cymbaluk
article en

Abstract

The INHALE-1 extension phase showed no safety concerns. Although HbA1c levels deteriorated slightly during the study, in view of the safety profile and increased patient satisfaction in the RCT portion of the trial, TI may be a useful treatment option for some pediatric patients with diabetes, particularly for those who choose not to or are unable to use an AID system.

Diabetes Technology & Therapeutics
Alfred I. duPont Hospital for Children (US), Children's Hospital of Philadelphia (US), Children's Hospital of Los Angeles (US), Emory University (US), Medical College of Wisconsin (US), Community Health Systems - Dupont Hospital (US), University of Florida (US), Rady Children's Hospital-San Diego (US), Nemours Children's Health System (US), Buffalo Medical Group (US), Jaeb Center for Health Research (US), Iowa Diabetes and Endocrinology Research Center (US), Rainbow Babies & Children's Hospital (US), University at Buffalo, State University of New York (US), The University of Texas Southwestern Medical Center (US)
Good health and well-being
Openalex Percentile: Top 66%
Inhalation and Respiratory Drug Delivery
DOISourceOpenAlex
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Inhaled Technosphere Insulin in Children with Diabetes: The INHALE-1 Extension Study — Patrick C. Hanley, KRISTINA COSSEN, et al. · Diabetes Technology & Therapeutics (2026) | TGRS Research Map | TGRS