Repeatability of Metrics of Skin Microvascular Function at Pressure Injury-Prone Sites Using a Direct Pressure and Heating Protocol

This study presents a reproducible protocol for assessing pressure-induced microvascular compromise, capturing responses from complete vascular occlusion to peak thermal-pressure hyperaemic vasodilation. Applied at the sacrum and heel, it offers a quantifiable, non-invasive tool to investigate pressure injury risk in vulnerable populations. It also supports future evaluations of support surfaces, offloading strategies, and novel therapeutic interventions to improve tissue pressure tolerance.

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Publication Details

Journal
Journal of Vascular Research
Published
2026-02-05
DOI
https://doi.org/10.1159/000550214
Primary Topic
Pressure Ulcer Prevention and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Repeatability of Metrics of Skin Microvascular Function at Pressure Injury-Prone Sites Using a Direct Pressure and Heating Protocol

Sven P. Hoekstra, Alex Lloyd, Mike J Fray, Vicky L. Tolfrey et al.
Journal of Vascular Research
Pressure Ulcer Prevention and Management
article

Repeatability of Metrics of Skin Microvascular Function at Pressure Injury-Prone Sites Using a Direct Pressure and Heating Protocol

Sven P. Hoekstra, Alex Lloyd, Mike J Fray, Vicky L. Tolfrey, Jo Barnes (1258872), Alexander Robertson
article en

Abstract

This study presents a reproducible protocol for assessing pressure-induced microvascular compromise, capturing responses from complete vascular occlusion to peak thermal-pressure hyperaemic vasodilation. Applied at the sacrum and heel, it offers a quantifiable, non-invasive tool to investigate pressure injury risk in vulnerable populations. It also supports future evaluations of support surfaces, offloading strategies, and novel therapeutic interventions to improve tissue pressure tolerance.

Journal of Vascular Research
Loughborough University (GB), St. Mary's University, Texas (US), Chesterfield Royal Hospital NHS Foundation Trust (GB), Chartered Institute of Ergonomics and Human Factors (GB)
Good health and well-being
Openalex Percentile: Top 64%
Pressure Ulcer Prevention and Management
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