Modified Dachengqi Decoction ameliorates sepsis-induced lung injury via the gut microbiota-bile acid axis
MDD can alleviate LPS-induced SI-ALI by modulating the gut microbiota-bile acid metabolism, activating FXR, and thereby suppressing the TLR4/MYD88-mediated inflammatory cascade and NETs generation.
Authors
- Peiyao Huang
- Lukui Chen (ORCID: https://orcid.org/0000-0002-8075-8369)
- Ya Li (ORCID: https://orcid.org/0000-0001-7347-386X)
- Ye Ye
- Bojun Chen
- Yuchao Feng
- Liyuan Yu
- Lulu Wu
- Weihang Peng
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- Jiangsu Provincial Academy of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-02-06
- DOI
- https://doi.org/10.3389/fcimb.2026.1661639
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00