Exploratory analysis of the 2-year changes in knee cartilage thickness and transverse relaxation time (T2) in ACL-injured versus healthy participants

ACL-injured knees displayed greater cartilage thinning, particularly using location-independent measures. Change in T2, in contrast, was limited and not specific to injury. Our findings underscore the need for relevant thresholds of cartilage thickness and T2 changes, to define early OA.

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Publication Details

Journal
Osteoarthritis and Cartilage Open
Published
2026-02-06
DOI
https://doi.org/10.1016/j.ocarto.2026.100755
Primary Topic
Knee injuries and reconstruction techniques
Type
article
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article

Exploratory analysis of the 2-year changes in knee cartilage thickness and transverse relaxation time (T2) in ACL-injured versus healthy participants

Annegret Mündermann, Oliver Bieri, Wolfgang Wirth, Corina Nüesch et al.
Osteoarthritis and Cartilage Open
Knee injuries and reconstruction techniques
article

Exploratory analysis of the 2-year changes in knee cartilage thickness and transverse relaxation time (T2) in ACL-injured versus healthy participants

Annegret Mündermann, Oliver Bieri, Wolfgang Wirth, Corina Nüesch, Christian Egloff, Felix Eckstein, Simon Herger
article en

Abstract

ACL-injured knees displayed greater cartilage thinning, particularly using location-independent measures. Change in T2, in contrast, was limited and not specific to injury. Our findings underscore the need for relevant thresholds of cartilage thickness and T2 changes, to define early OA.

Osteoarthritis and Cartilage OpenVol. 8(1)
University of Basel (CH), Paracelsus Medical University (AT), University Hospital of Basel (CH), Schulthess-Klinik (CH)
Zero hunger
Openalex Percentile: Top 65%
Knee injuries and reconstruction techniques
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