Tricyclic Antidepressants suppress sleep in <i>Caenorhabditis elegans</i>
This is the first high-throughput screen for chemicals modulating SIS. Elucidating the mechanism by which AMI and other chemicals regulate sleep will lead to new biological insights regarding the mechanisms of sleep.
Authors
- Marisa Petticord (ORCID: https://orcid.org/0000-0002-4160-4332)
- David M. Raizen (ORCID: https://orcid.org/0000-0001-5935-0476)
- D. Schultz (ORCID: https://orcid.org/0000-0002-7890-8815)
- Zipporah M Robinson
- Joel T Woolley
- William J Lee
Institutions
- University of Pennsylvania (US)
Publication Details
- Journal
- SLEEP
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1093/sleep/zsag034
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00