Prevalence of chromosomal abnormalities and polymorphisms in 4,672 infertile patients undergoing assisted reproductive techniques in the United Arab Emirates population

This study represents the largest cytogenetic dataset on infertile patients in the UAE and the wider Gulf region, offering population-specific insights into chromosomal determinants of infertility. Routine karyotyping especially for azoospermic men remains essential for accurate diagnosis, informed counseling, and optimized ART planning. These findings provide UAE-specific prevalence data and support risk-stratified counseling; however, the consanguinity analysis reflects marital consanguinity within couples and does not assess parental consanguinity or causality.