The role of antibody-drug conjugates in the treatment of lung cancer

Over the las0t decades, lung cancer treatment has improved immensely, mainly due to the incorporation of new targeted treatments and immunotherapy. A relatively new and potentially highly effective class of drugs, antibody-drug conjugates (ADCs), has been introduced to the clinical setting and is currently under intense investigation, alone and in combination with other molecules. This study aims to summarize the latest data on ADCs for lung cancer treatment and to analyze their potential, toxicity profile, and challenges.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-05
DOI
https://doi.org/10.3389/fonc.2026.1757564
Primary Topic
HER2/EGFR in Cancer Research
Type
article
Field-Weighted Citation Impact
0.00
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article

The role of antibody-drug conjugates in the treatment of lung cancer

Tanya Zlatanova, Urška Janžič, Aynura Changalova
Frontiers in Oncology
HER2/EGFR in Cancer Research
article

The role of antibody-drug conjugates in the treatment of lung cancer

Tanya Zlatanova, Urška Janžič, Aynura Changalova
article en

Abstract

Over the las0t decades, lung cancer treatment has improved immensely, mainly due to the incorporation of new targeted treatments and immunotherapy. A relatively new and potentially highly effective class of drugs, antibody-drug conjugates (ADCs), has been introduced to the clinical setting and is currently under intense investigation, alone and in combination with other molecules. This study aims to summarize the latest data on ADCs for lung cancer treatment and to analyze their potential, toxicity profile, and challenges.

Frontiers in OncologyVol. 16
University of Ljubljana (SI), Tokuda Hospital (BG), Uni Research (Norway) (NO), University Clinic of Pulmonary and Allergic Diseases Golnik (SI)
Good health and well-being
Openalex Percentile: Top 64%
HER2/EGFR in Cancer Research
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The role of antibody-drug conjugates in the treatment of lung cancer — Tanya Zlatanova, Urška Janžič, et al. · Frontiers in Oncology (2026) | TGRS Research Map | TGRS