The 7S Domain of Type IV Collagen as a Noninvasive Surrogate of Portal Hypertension
4COL7S is the most reliable noninvasive biomarker for predicting HRV. Its superior diagnostic accuracy supports its use as a practical surrogate for HVPG and as a valuable tool in clinical risk stratification for variceal bleeding.
Authors
- Hiroyuki Masuda (ORCID: https://orcid.org/0000-0003-3288-0236)
- Akira Mitoro
- Tadashi Namisaki (ORCID: https://orcid.org/0000-0002-3158-5318)
- Hitoshi YOSHIJI
- Shohei Asada (ORCID: https://orcid.org/0000-0001-5997-4799)
- Hiroaki Takaya (ORCID: https://orcid.org/0000-0002-4990-7573)
- Akihiko Shibamoto
- Masayoshi Takami
- Norihisa Nishimura (ORCID: https://orcid.org/0000-0002-6295-3283)
- Yukihisa Fujinaga (ORCID: https://orcid.org/0000-0003-2402-574X)
- Yuki Tsuji
- Shinya Sato
- Koh Kitagawa
- Satoshi Iwai
- Takashi Inoue
- Kosuke Kaji
- Kiyoshi Asada
Institutions
- Nara Medical University (JP)
Publication Details
- Journal
- Hepatology Research
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1111/hepr.70134
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00