Failure of Endophthalmitis Prophylaxis: A Laboratory Model Comparing Antibiotics and Bacterial Loads

High bacterial loads can multiply uncontrollably in the presence of antibiotics which are effective when the bacterial load is lower; this underscores the importance of uncontaminated equipment and ocular surface antisepsis. Broadest coverage against common postoperative endophthalmitis pathogens was demonstrated by moxifloxacin and ceftazidime.