Shared genetic architecture of psychoactive substance use and pan-cancer: insights from a large‑scale genome‑wide cross‑trait analysis
In summary, we identified a shared genetic architecture comprising pleiotropic cerebellar hub genes linking PSU-cancer trait pairs and described potential interventional drugs.
Authors
- K. Unger
- Jiahang Song (ORCID: https://orcid.org/0000-0001-7858-2096)
- Olivier Gires (ORCID: https://orcid.org/0000-0002-2292-7064)
- Nikolaus Alexander Haas
- Pengzhu Li
- Martin Canis
Institutions
- LMU Klinikum (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- BMC Medicine
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1186/s12916-026-04677-3
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00