Switching and Sniffing around the β-globin cluster

In this issue of Blood, Bagchi et al 1 show how the -like globin genes may be regulated by "Switch-Sniff" (switch/sucrose nonfermentable) chromatin remodeling complexes and suggest that this may provide new targets for therapy in globin gene disorders.

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Publication Details

Journal
Blood
Published
2026-02-05
DOI
https://doi.org/10.1182/blood.2025032184
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Switching and Sniffing around the β-globin cluster

Kinam Gupta, Douglas Higgs
Blood
Hemoglobinopathies and Related Disorders
article

Switching and Sniffing around the β-globin cluster

Kinam Gupta, Douglas Higgs
article en

Abstract

In this issue of Blood, Bagchi et al 1 show how the -like globin genes may be regulated by "Switch-Sniff" (switch/sucrose nonfermentable) chromatin remodeling complexes and suggest that this may provide new targets for therapy in globin gene disorders.

BloodVol. 147(6)
University of Oxford (GB), MRC Weatherall Institute of Molecular Medicine (GB)
Climate action
Openalex Percentile: Top 65%
Hemoglobinopathies and Related Disorders
DOIOpen Access PDFOpenAlex
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