Prediction models for incident stroke in the community: a systematic review and meta-analysis of predictive performance

Many models have been derived for stroke prediction, however, they are rarely externally validated, and studies are limited by a high risk of bias, poor reporting of calibration and a lack of clinical utility analysis or prospective validation. Thus, the evidence base is insufficient to translate these models to clinical practice.

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Publication Details

Journal
European Heart Journal - Digital Health
Published
2025-12-11
DOI
https://doi.org/10.1093/ehjdh/ztaf147
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Prediction models for incident stroke in the community: a systematic review and meta-analysis of predictive performance

Harriet Larvin, Tanina Younsi, Elizabeth Romer, Jianhua Wu et al.
European Heart Journal - Digital Health
Acute Ischemic Stroke Management
article

Prediction models for incident stroke in the community: a systematic review and meta-analysis of predictive performance

Harriet Larvin, Tanina Younsi, Elizabeth Romer, Jianhua Wu, Chris Wilkinson, Mohammad Haris, A Cameron, G F Romiti, C P Gale, Gregory Y H Lip
article en

Abstract

Many models have been derived for stroke prediction, however, they are rarely externally validated, and studies are limited by a high risk of bias, poor reporting of calibration and a lack of clinical utility analysis or prospective validation. Thus, the evidence base is insufficient to translate these models to clinical practice.

European Heart Journal - Digital HealthVol. 7(2)
University of Leeds (GB), Medical University of Białystok (PL), University of Liverpool (GB), Queen Mary University of London (GB), Leeds Teaching Hospitals NHS Trust (GB), James Cook University Hospital (GB), South Tees Hospitals NHS Foundation Trust (GB), Airedale NHS Foundation Trust (GB), Liverpool Heart and Chest Hospital (GB), Leeds Dental Hospital (GB), University of York (GB), Liverpool John Moores University (GB), Hull York Medical School (GB), University of Glasgow (GB), Sapienza University of Rome (IT), Aalborg University (DK)
Reduced inequalities
Openalex Percentile: Top 26%
Acute Ischemic Stroke Management
DOIOpen Access PDFOpenAlex
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