Assessment of macrolide resistance in the respiratory tract of preterm-born infants during treatment with azithromycin in the AZTEC clinical trial

Macrolide-resistant genes were noticeably prevalent in the placebo group, with minimal increase with azithromycin treatment, suggesting that, regardless of the additional use of azithromycin, judicious use of antibiotics is required in preterm-born infants.

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Publication Details

Journal
Thorax
Published
2026-02-04
DOI
https://doi.org/10.1136/thorax-2025-224094
Primary Topic
Neonatal Respiratory Health Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessment of macrolide resistance in the respiratory tract of preterm-born infants during treatment with azithromycin in the AZTEC clinical trial

Julian Roberto Marchesi, Claudia Consoli, Ali F. Aboklaish, David J. Gallacher et al.
Thorax
Neonatal Respiratory Health Research
article

Assessment of macrolide resistance in the respiratory tract of preterm-born infants during treatment with azithromycin in the AZTEC clinical trial

Julian Roberto Marchesi, Claudia Consoli, Ali F. Aboklaish, David J. Gallacher, W. John Watkins, Sailesh Kotecha, John Lowe
article en

Abstract

Macrolide-resistant genes were noticeably prevalent in the placebo group, with minimal increase with azithromycin treatment, suggesting that, regardless of the additional use of azithromycin, judicious use of antibiotics is required in preterm-born infants.

Thorax
University Hospital of Wales (GB), Imperial College London (GB), Cardiff University (GB)
Good health and well-being
Openalex Percentile: Top 66%
Neonatal Respiratory Health Research
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