OnabotulinumtoxinA blockade of the sphenopalatine ganglion in treatment-resistant chronic migraine (MiBlock): rationale, design and study protocol for a multi-centre, investigator initiated, randomised, quadruple-blinded placebo-controlled trial.

Authors

Irina Aschehoug
Lise Rystad Øie (ORCID: https://orcid.org/0000-0001-9844-4651)
Erling Tronvik (ORCID: https://orcid.org/0000-0001-6059-0151)
Melanie Rae Simpson (ORCID: https://orcid.org/0000-0003-2763-6343)
Sozaburo Hara (ORCID: https://orcid.org/0000-0003-3942-1788)
Daniel Fossum Bratbak (ORCID: https://orcid.org/0000-0001-8483-7489)
Øyvind Salvesen (ORCID: https://orcid.org/0000-0002-6145-8109)
Einar Tobias Vassbø Skalstad
Tore Wergeland

Institutions

Norwegian University of Science and Technology (NO)
St Olav's University Hospital (NO)

Publication Details

Journal: F1000Research
Published: 2026-02-05
DOI: https://doi.org/10.12688/f1000research.164241.2
Primary Topic: Migraine and Headache Studies
Type: article
Field-Weighted Citation Impact: 0.00

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article

OnabotulinumtoxinA blockade of the sphenopalatine ganglion in treatment-resistant chronic migraine (MiBlock): rationale, design and study protocol for a multi-centre, investigator initiated, randomised, quadruple-blinded placebo-controlled trial.

Irina Aschehoug, Lise Rystad Øie, Erling Tronvik, Melanie Rae Simpson et al.

Feb 5, 2026

F1000Research

Migraine and Headache Studies

article

OnabotulinumtoxinA blockade of the sphenopalatine ganglion in treatment-resistant chronic migraine (MiBlock): rationale, design and study protocol for a multi-centre, investigator initiated, randomised, quadruple-blinded placebo-controlled trial.

Irina Aschehoug, Lise Rystad Øie, Erling Tronvik, Melanie Rae Simpson, Sozaburo Hara, Daniel Fossum Bratbak, Øyvind Salvesen, Einar Tobias Vassbø Skalstad, Tore Wergeland

February 5, 2026article en

Abstract

No abstract available for this paper.

F1000ResearchVol. 14

Norwegian University of Science and Technology (NO), St Olav's University Hospital (NO)

Openalex Percentile: Top 67%

Migraine and Headache Studies

DOI Open Access PDF OpenAlex

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