Single‐cell analysis reveals cytotoxic and memory CD8 <sup>+</sup> T cells associated with prolonged survival in relapsed/refractory leukaemia patients after haplo+cord haematopoietic stem cell transplantation
Our results collectively demonstrate that a population of CD8<sup>+</sup> T cells with effector and memory properties contributes to improved survival in patients with R/R leukaemia receiving haplo+cord HSCT.
Authors
- Lin Tian (ORCID: https://orcid.org/0000-0001-5314-4188)
- Jinxian Dai
- Hui Li (ORCID: https://orcid.org/0000-0001-9198-3951)
- Zheyang Zhang (ORCID: https://orcid.org/0009-0006-3923-6864)
- Tao Chen (ORCID: https://orcid.org/0000-0003-1543-607X)
- Ping Chen (ORCID: https://orcid.org/0000-0003-0274-5674)
- Xiaofan Li (ORCID: https://orcid.org/0000-0003-4168-0068)
- Yuehua Chen (ORCID: https://orcid.org/0009-0006-1343-7449)
- Xiaohong Yuan (ORCID: https://orcid.org/0000-0003-0287-752X)
- Yiding Yang
- Mengsha Tong
- Ming Zhu
- Nainong Li
- Zhijuan Zhu
- Xianling Chen
- Ronghan Tang
- Fei Chen
- Hongli Lin
Institutions
- Fujian Medical University (CN)
- Jimei University (CN)
- Xiamen University (CN)
- Xiamen National Accounting Institute (CN)
- Xiamen Chang Gung Hospital (CN)
- Xiamen University of Technology (CN)
Publication Details
- Journal
- Clinical and Translational Medicine
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/ctm2.70529
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00