Gitelman and Bartter Syndrome in a Patient With Morbid Obesity: A Case Report and Literature Review

We present a case study of a 34-year-old man with morbid obesity and a suspected Bartter-Gitelman spectrum tubulopathy (without genetic confirmation), weighing 135 kg, and with a BMI of 42.5 kg/m<sup>2</sup>, who was referred to the metabolic and bariatric surgery department due to morbid obesity to address abnormal electrolyte levels. The clinical presentation suggested renal tubular salt wasting. Post-sleeve gastrectomy, the patient had sustained and prolonged normalization in his electrolytes without the use of any medications. This provides evidence of a possible relationship between metabolic surgery and renal tubular function. This case supports recognizing a suspected tubulopathy in candidates for metabolic surgery.

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Publication Details

Journal
Clinical Case Reports
Published
2026-02-01
DOI
https://doi.org/10.1002/ccr3.71903
Primary Topic
Ion Transport and Channel Regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

Gitelman and Bartter Syndrome in a Patient With Morbid Obesity: A Case Report and Literature Review

Mohammad Javad Ghamari, Narges Mesbah, Tooraj Zandbaf, Solmaz Hasani et al.
Clinical Case Reports
Ion Transport and Channel Regulation
article

Gitelman and Bartter Syndrome in a Patient With Morbid Obesity: A Case Report and Literature Review

Mohammad Javad Ghamari, Narges Mesbah, Tooraj Zandbaf, Solmaz Hasani, Alireza Rezapanah
article en

Abstract

We present a case study of a 34-year-old man with morbid obesity and a suspected Bartter-Gitelman spectrum tubulopathy (without genetic confirmation), weighing 135 kg, and with a BMI of 42.5 kg/m<sup>2</sup>, who was referred to the metabolic and bariatric surgery department due to morbid obesity to address abnormal electrolyte levels. The clinical presentation suggested renal tubular salt wasting. Post-sleeve gastrectomy, the patient had sustained and prolonged normalization in his electrolytes without the use of any medications. This provides evidence of a possible relationship between metabolic surgery and renal tubular function. This case supports recognizing a suspected tubulopathy in candidates for metabolic surgery.

Clinical Case ReportsVol. 14(2)
Mashhad University of Medical Sciences (IR), Islamic Azad University, Mashhad (IR)
Openalex Percentile: Top 66%
Ion Transport and Channel Regulation
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Gitelman and Bartter Syndrome in a Patient With Morbid Obesity: A Case Report and Literature Review — Mohammad Javad Ghamari, Narges Mesbah, et al. · Clinical Case Reports (2026) | TGRS Research Map | TGRS