Characterizing two subtypes of osteosarcoma using G2M checkpoint-related genes and revealing its immune landscape
This study elucidates the prognostic and immune microenvironmental characteristics of G2M checkpoint-related genes in OS, and validates the critical oncogenic function of KIF20B and its regulatory role in drug sensitivity. This study provides novel potential targets and strategies for molecular subtyping and targeted therapy of OS.
Authors
- Hong Song (ORCID: https://orcid.org/0000-0002-0113-0697)
- Zhuobin Yang
Institutions
- Zunyi Medical University (CN)
- Affiliated Hospital of Zunyi Medical College (CN)
Publication Details
- Journal
- Molecular Immunology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1016/j.molimm.2026.01.014
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00