Myeloid-derived suppressor cells and their subsets serve as potential biomarkers for the progression of brucellosis
These findings expand the current understanding of persistent Brucella infection, and highlight that TLR4<sup>+</sup> and PD-L1<sup>+</sup> MDSCs hold potential as candidate biomarkers for assessing the severity and progression of brucellosis.
Authors
- Yibeibaihan Maimaiti
- F B Zhang
- Jianbing Ding
- Na Chen (ORCID: https://orcid.org/0000-0002-3611-7804)
- YueJie Zhu
- Xinxin Qi
- Huidong Shi
- Juan Shi
Institutions
- Xinjiang Medical University (CN)
- Xinjiang Production and Construction Corps (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
- First Affiliated Hospital of Shihezi University Medical College (CN)
- Second Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.3389/fmicb.2026.1730300
- Primary Topic
- Brucella: diagnosis, epidemiology, treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China