Interpretable AI-driven prediction of early postoperative recurrence in locally advanced rectal cancer using the Systemic Inflammatory–Nutritional Index (SINTI): A multi-center study and clinical web tool
This interpretable AI framework demonstrates the potential to bridge data-driven modeling and clinical decision support, offering a transparent, potentially deployable solution for post-NCRT recurrence risk prediction following further prospective validation.
Authors
- Ziye Zhuang (ORCID: https://orcid.org/0009-0001-0128-1778)
- Tengyi Peng (ORCID: https://orcid.org/0000-0001-8457-3225)
- Ye Wang (ORCID: https://orcid.org/0009-0009-9048-3838)
- Xingrong Lu
- Guoxian Guan
- Zhen Pan
- Bin Chen
- Shoufeng Li
Institutions
- Fujian Medical University (CN)
- National Hospital (IN)
- First Affiliated Hospital of Fujian Medical University (CN)
- Union Hospital (CN)
Publication Details
- Journal
- International Journal of Colorectal Disease
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1007/s00384-026-05081-2
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China