The effect of melatonin supplementation on lipid profile, oxidative stress, inflammatory marker, and sleep quality in patients with chronic kidney disease: a GRADE assessed meta-analysis

Supplementing with MLT in CKD can gently raise HDL-C levels, decrease oxidative stress, and improve sleep quality. While these effects are encouraging, more extensive and carefully planned clinical trials are necessary to verify the actual benefits.

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Publication Details

Journal
Frontiers in Nutrition
Published
2026-02-06
DOI
https://doi.org/10.3389/fnut.2026.1772877
Primary Topic
Circadian rhythm and melatonin
Type
article
Field-Weighted Citation Impact
0.00
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article

The effect of melatonin supplementation on lipid profile, oxidative stress, inflammatory marker, and sleep quality in patients with chronic kidney disease: a GRADE assessed meta-analysis

Ashishkumar Kyada, Atheer Khdyair Hamad, Mahmood Jasem Jawad, Waam Mohammed Taher et al.
Frontiers in Nutrition
Circadian rhythm and melatonin
article

The effect of melatonin supplementation on lipid profile, oxidative stress, inflammatory marker, and sleep quality in patients with chronic kidney disease: a GRADE assessed meta-analysis

Ashishkumar Kyada, Atheer Khdyair Hamad, Mahmood Jasem Jawad, Waam Mohammed Taher, Morug Salih Mahdi, Mariem Alwan, Zahraa Sabah Ghnim, Hamidah Abu Bakar, Aziz Kubaev, Dukhbhanjan Singh, Neeraj Khare, Qamar Abuhassan
article en

Abstract

Supplementing with MLT in CKD can gently raise HDL-C levels, decrease oxidative stress, and improve sleep quality. While these effects are encouraging, more extensive and carefully planned clinical trials are necessary to verify the actual benefits.

Frontiers in NutritionVol. 13
University of Jordan (JO), Al Noor Hospitals (AE), Management and Science University (MY), NIMS University (IN), Ahl Al Bayt University (IQ), National University of Science and Technology (ZW), Marwadi University (IN), Baba Farid University of Health Sciences (IN), Palestine Ahliya University (PS), Samarkand State Medical Institute (UZ), Chitkara University (IN)
Good health and well-being
Openalex Percentile: Top 62%
Circadian rhythm and melatonin
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