Circulating miR-326 and miR-532-3p: novel biomarkers for early gestational diabetes mellitus detection with high diagnostic accuracy

This study provides compelling evidence for circulating miR-326 and miR-532-3p as a synergistic pair of biomarkers for GDM. Their high diagnostic accuracy and mechanistic insights into metabolic dysregulation position them as a promising complementary tool for early GDM risk assessment and for understanding GDM pathophysiology.

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Publication Details

Journal
Journal of Endocrinological Investigation
Published
2026-02-05
DOI
https://doi.org/10.1007/s40618-026-02829-z
Primary Topic
Gestational Diabetes Research and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Circulating miR-326 and miR-532-3p: novel biomarkers for early gestational diabetes mellitus detection with high diagnostic accuracy

Taosheng Huang, Zhikun Liang, Bing-Yi Xu, Hui-Zhen Lin et al.
Journal of Endocrinological Investigation
Gestational Diabetes Research and Management
article

Circulating miR-326 and miR-532-3p: novel biomarkers for early gestational diabetes mellitus detection with high diagnostic accuracy

Taosheng Huang, Zhikun Liang, Bing-Yi Xu, Hui-Zhen Lin, S. Joseph Huang, Long Xie, Jin-Lin Tan, Yong Yang, Jun-Ju Huang, Shi-Han Ruan, Qi-Guang Wang, Zhi-Shen Wu, Yan Huang, Ze-Fan Ruan
article en

Abstract

This study provides compelling evidence for circulating miR-326 and miR-532-3p as a synergistic pair of biomarkers for GDM. Their high diagnostic accuracy and mechanistic insights into metabolic dysregulation position them as a promising complementary tool for early GDM risk assessment and for understanding GDM pathophysiology.

Journal of Endocrinological Investigation
Fujian Medical University (CN), Hunan Normal University (CN), The Centre for Health (New Zealand) (NZ), Guangzhou Mechanical Engineering Research Institute (China) (CN), Ministry of Health (TT), China Shenhua Energy (China) (CN), Hunan Provincial People's Hospital (CN), Huazhong University of Science and Technology (CN), Putian University (CN), Newcastle University (GB)
Fujian Medical University
Good health and well-being
Openalex Percentile: Top 68%
Gestational Diabetes Research and Management
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