Taurochenodeoxycholic Acid Activates Calcium Signaling to Protect Against Fuchs’ Endothelial Corneal Dystrophy
TCDCA demonstrated a protective effect on corneal endothelial cells during the pathogenesis of FECD. Therefore, TCDCA may be a promising novel therapeutic target for attenuating the progression of FECD.
Authors
- S. C. Yao (ORCID: https://orcid.org/0000-0002-2027-8523)
- Xiaoyu Li (ORCID: https://orcid.org/0009-0002-3652-620X)
- Shengqian Dou
- Can Zhao
- Yujie Qiao
- Qingjun Zhou
- Qun Wang
Institutions
- Shandong Eye Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1167/iovs.67.2.16
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00