Sex differences in the clinical and surgical management after intracerebral hemorrhage: A post hoc analysis of the INTERACT3 clinical trial
Following acute ICH, females generally receive similar active acute care interventions as males, except for observed differences in access to assisted feeding and decision to withdraw from active care. These findings suggest that equal access to ICH interventions for females and males is feasible and exists in some settings. However, disparities in certain key interventions remain and present actionable opportunities for improvement. Further research is needed to explore not only access but also the timing and frequency of these interventions.Data access statement:Individual, de-identified participant data used in these analyses will be shared on request from any qualified investigator after the approval of a protocol and signed data access agreement via both the trial steering committee and the research office of The George Institute for Global Health (Sydney, NSW, Australia).
Authors
- A. de Silva
- Menglu Ouyang (ORCID: https://orcid.org/0000-0001-7917-6858)
- Anderson Craig
- X. Chen
- Alejandra Malavera
- OCTÁVIO MARQUES PONTES-NETO (ORCID: https://orcid.org/0000-0003-0317-843X)
- Carlos Abanto Argomedo
- Ma.Ignacia Allende (ORCID: https://orcid.org/0009-0005-7076-1539)
- T. Thi Ngo Nguyen (ORCID: https://orcid.org/0009-0006-9558-7626)
- F. REVIVAL Investigators
- Mohammad Wasay
- Lili Song
- Katie Harris
- Laurent Billot
- C You
- X Hu
- Antonio Arauz-Góngora
- qiang Li
- Lu Ma
- Kolawole Wahab
- Jeyaraj Pandian
- Xi Li
Institutions
- Aga Khan University (PK)
- Universidad del Desarrollo (CL)
- University of Kelaniya (LK)
- Christian Medical College, Vellore (IN)
- Universidade de São Paulo (BR)
- Sichuan University (CN)
- Fudan University (CN)
- Clínica Alemana (CL)
- UNSW Sydney (AU)
- Shanghai Institute for Science of Science (CN)
- West China Hospital of Sichuan University (CN)
- Christian Medical College (IN)
- The George Institute for Global Health (AU)
- Instituto Nacional de Neurología y Neurocirugía (MX)
- University of Ilorin Teaching Hospital (NG)
- Clinics Hospital of Ribeirão Preto (BR)
- Pham Ngoc Thach Hospital (VN)
- Shanghai Center for Brain Science and Brain-Inspired Technology (CN)
- Instituto Nacional de Ciencias Neurológicas
Publication Details
- Journal
- International Journal of Stroke
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1177/17474930261423639
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00