Investigating the Role of A20 in Respiratory Syncytial Virus Immunopathogenesis in a BALB/c Mouse Model
A20 downregulation exacerbates inflammation and lung injury following RSV infection, highlighting its critical role in immune regulation during the virus infection. Further studies employing targeted molecular delivery systems and human airway organoid models are warranted to evaluate the therapeutic potential of modulating A20 in RSV disease.
Authors
- Alireza Tahamtan (ORCID: https://orcid.org/0000-0001-7680-5698)
- Saeed Samadizadeh (ORCID: https://orcid.org/0000-0002-0811-6820)
- Mohammad Yasaghi
- Hadi Razavi Nikoo
- Vahid Salimi
- Ahad Yamchi
Institutions
- Queen's University Belfast (GB)
- Iran University of Medical Sciences (IR)
- Golestan University (IR)
- Golestan University of Medical Sciences (IR)
- Gorgan University of Agricultural Sciences and Natural Resources (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/iid3.70337
- Primary Topic
- NF-κB Signaling Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Medical Research Development