Serum miR-381-3p: Diagnostic Role and Mechanisms in Liver Transplant Ischemia-reperfusion Injury
miR-381-3p exacerbates post-transplant HIR by directly targeting JAK2, amplifying inflammation and oxidative stress. Thus, our findings nominate serum miR-381-3p as a promising non-invasive biomarker and suggest its potential as a therapeutic target for mitigating HIR injury.
Authors
- Xiaobin Chi (ORCID: https://orcid.org/0009-0004-2194-3849)
- Lizhi Lv (ORCID: https://orcid.org/0000-0003-4265-4312)
- Ziang Chen (ORCID: https://orcid.org/0000-0002-8298-5223)
- Jianda Yu (ORCID: https://orcid.org/0009-0001-1089-2343)
- Zerun Lin
- Yongbiao Chen
- Qiucheng Cai
- Honghuan Lin
Institutions
- Mengchao Hepatobiliary Hospital (CN)
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.14218/jcth.2025.00571
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00