ECM remodeling-associated immune signatures and hub proteins: predictive markers and therapeutic targets for metastatic gastric cancer

This study not only reveals the complexity of ECM remodeling in the microenvironment of gastric cancer but also provides new perspectives and potential targets for future gastric cancer treatment and brings opportunities for the development of new therapeutics, which are expected to overcome the challenge of cancer metastasis.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-02-06
DOI
https://doi.org/10.3389/fimmu.2026.1765095
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
0.00
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article

ECM remodeling-associated immune signatures and hub proteins: predictive markers and therapeutic targets for metastatic gastric cancer

Ke Zhao, Xinyue Hu, Yaoqiang Shi, Zhongjian Liu et al.
Frontiers in Immunology
Single-cell and spatial transcriptomics
article

ECM remodeling-associated immune signatures and hub proteins: predictive markers and therapeutic targets for metastatic gastric cancer

Ke Zhao, Xinyue Hu, Yaoqiang Shi, Zhongjian Liu, Yi Sun
article en

Abstract

This study not only reveals the complexity of ECM remodeling in the microenvironment of gastric cancer but also provides new perspectives and potential targets for future gastric cancer treatment and brings opportunities for the development of new therapeutics, which are expected to overcome the challenge of cancer metastasis.

Frontiers in ImmunologyVol. 17
Kunming University of Science and Technology (CN), Kunming Medical University (CN), First People's Hospital of Yunnan Province (CN)
Openalex Percentile: Top 66%
Single-cell and spatial transcriptomics
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