Symptom burden, viral load, and antibody response to ancestral SARS-CoV-2 strain [D614G] in an outpatient household cohort

Fever, anosmia, as well as asymptomatic infection were common features of COVID-19 non-severe illness when the D614G variant circulated in the US, before the availability of vaccines or outpatient therapies. Antibody levels following acute infection were linked to the development of symptoms of PASC 8-10 months later.

Authors

Institutions

Publication Details

Journal
PLoS ONE
Published
2026-02-05
DOI
https://doi.org/10.1371/journal.pone.0313467
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Symptom burden, viral load, and antibody response to ancestral SARS-CoV-2 strain [D614G] in an outpatient household cohort

Sydney Mason, Gabrielle Streeter, C. Andrew Basham, K. Tompkins et al.
PLoS ONE
Long-Term Effects of COVID-19
article

Symptom burden, viral load, and antibody response to ancestral SARS-CoV-2 strain [D614G] in an outpatient household cohort

Sydney Mason, Gabrielle Streeter, C. Andrew Basham, K. Tompkins, Maureen Whittelsey, Srijana Chhetri, Tia Belvin, Jessica T. Lin, Lakshmanane Premkumar, Tyler Rapp, Christy Litel, Carla Cerami, Kelly Lin
article en

Abstract

Fever, anosmia, as well as asymptomatic infection were common features of COVID-19 non-severe illness when the D614G variant circulated in the US, before the availability of vaccines or outpatient therapies. Antibody levels following acute infection were linked to the development of symptoms of PASC 8-10 months later.

PLoS ONEVol. 21(2)
University of North Carolina at Chapel Hill (US), MRC Unit the Gambia (GM)
Good health and well-being
Openalex Percentile: Top 66%
Long-Term Effects of COVID-19
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.