Bufalin Inhibits Cytokine Storm by Regulating TLR4/TLR3 Signaling Pathway
These findings not only support the pharmacological basis of using toad to treat inflammatory diseases in the Chinese medical history, but also provide a promising anti-inflammatory drug candidate for future clinical application.
Authors
- Chang Li (ORCID: https://orcid.org/0000-0002-3267-1859)
- Tian Fang (ORCID: https://orcid.org/0000-0001-5388-1081)
- X. Zhang
- Xuebin Zhu (ORCID: https://orcid.org/0000-0001-9484-8253)
- Xixi Liu Liu
- Weiguang Zhang
- Xingbin Dai
- Zhongxiao Hu
- Zuqiong Xu
- Reaila Jianati
- Biqing Chen
- Jing Yang
Institutions
- Nanjing University of Chinese Medicine (CN)
- Jiujiang First People's Hospital (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
- Xi’an Jiaotong-Liverpool University (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/iid3.70318
- Primary Topic
- Venomous Animal Envenomation and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jiangsu Commission of Health
- National Natural Science Foundation of China
- Government of Jiangsu Province