Ginkgetin Alleviates Doxorubicin-Induced Heart Failure by Regulating Mitochondrial Dysfunction Through the AMPK/Sirt1/NF-κB Signaling Pathway
GK protects against DOX-induced HF by activating AMPK/Sirt1 and inhibiting NF-κB signaling, thereby mitigating OS, inflammation, apoptosis, and mitochondrial dysfunction.
Authors
- Yubo Peng
- Hang Liu (ORCID: https://orcid.org/0000-0001-6194-9250)
- Yanfu Wang
- Yan Zhang
- Xinyu Ren
- Wei Li
Institutions
- Beijing Chest Hospital (CN)
- Aviation General Hospital (CN)
Publication Details
- Journal
- Balkan Medical Journal
- Published
- 2026-02-06
- DOI
- https://doi.org/10.4274/balkanmedj.galenos.2026.2025-11-113
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 0.00