Multicenter prospective phase II study of decitabine priming with low-dose idarubicin, cytarabine, and G-CSF in children with refractory or relapsed acute myeloid leukemia

No standard salvage regimen exists for relapsed/refractory (R/R) pediatric AML. In this prospective, multicenter Phase II trial, 101 evaluable patients (.

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Publication Details

Journal
Haematologica
Published
2026-02-05
DOI
https://doi.org/10.3324/haematol.2025.289170
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Multicenter prospective phase II study of decitabine priming with low-dose idarubicin, cytarabine, and G-CSF in children with refractory or relapsed acute myeloid leukemia

Y H Wang, R C Ribeiro, Jixia Luo, Yeting He et al.
Haematologica
Acute Myeloid Leukemia Research
article

Multicenter prospective phase II study of decitabine priming with low-dose idarubicin, cytarabine, and G-CSF in children with refractory or relapsed acute myeloid leukemia

Y H Wang, R C Ribeiro, Jixia Luo, Yeting He, Ningling Wang, Shaoyan Hu, Yuan Zhang, Wen Zhang, Liyan Fan, Xiuli Ju, Ning Liao, Xueju Xu, Jun Lu, Yixin Hu, Xue Han, Li Gao, Hongsheng Wang, Xiaowen Zhai, Hailong He, Cheng Cheng, Hua Jiang, Linhai Yang, Yong Zhuang, Peifang Xiao, Hongjun Liu, Jie Li
article en

Abstract

No standard salvage regimen exists for relapsed/refractory (R/R) pediatric AML. In this prospective, multicenter Phase II trial, 101 evaluable patients (.

Haematologica
University of Science and Technology of China (CN), St. Jude Children's Research Hospital (US), Soochow University (TW), Anhui Medical University (CN), Soochow University (CN), Guangzhou Women and Children Medical Center (CN), First Affiliated Hospital of GuangXi Medical University (CN), Kaifeng City Children's Hospital (CN), Second Affiliated Hospital of Anhui Medical University (CN), First Affiliated Hospital of Soochow University (CN), First Affiliated Hospital of Zhengzhou University (CN), Children's Hospital of Fudan University (CN), Qilu Hospital of Shandong University (CN), Guangzhou Medical University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 63%
Acute Myeloid Leukemia Research
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