Diverse Terpenoids From <i>Cryptomeria japonica</i>

Three previously undescribed diterpenoids and a new sesquiterpenoid, along with 31 known terpenoids, were isolated from the leaves and twigs of Cryptomeria japonica. Their structures were elucidated by spectroscopic data and ECD calculations. Antibacterial screening of all isolated compounds was conducted. Compounds 15 and 16 exhibited modest activity against drug-resistant Staphylococcus aureus subsp. aureus ATCC29213, with MIC<sub>50</sub> values of 3.57 ± 0.03 and 8.69 ± 0.03 µM, respectively.

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Publication Details

Journal
Chemistry & Biodiversity
Published
2026-02-01
DOI
https://doi.org/10.1002/cbdv.70965
Primary Topic
Biological Activity of Diterpenoids and Biflavonoids
Type
article
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article

Diverse Terpenoids From Cryptomeria japonica

Ling Xu, X. Yuan, Zhi‐Ping Zhou, Qin‐Shi Zhao
Chemistry & Biodiversity
Biological Activity of Diterpenoids and Biflavonoids
article

Diverse Terpenoids From Cryptomeria japonica

Ling Xu, X. Yuan, Zhi‐Ping Zhou, Qin‐Shi Zhao
article en

Abstract

Three previously undescribed diterpenoids and a new sesquiterpenoid, along with 31 known terpenoids, were isolated from the leaves and twigs of Cryptomeria japonica. Their structures were elucidated by spectroscopic data and ECD calculations. Antibacterial screening of all isolated compounds was conducted. Compounds 15 and 16 exhibited modest activity against drug-resistant Staphylococcus aureus subsp. aureus ATCC29213, with MIC<sub>50</sub> values of 3.57 ± 0.03 and 8.69 ± 0.03 µM, respectively.

Chemistry & BiodiversityVol. 23(2)
Shenyang Pharmaceutical University (CN), Kunming Institute of Botany (CN), University of Chinese Academy of Sciences (CN)
Openalex Percentile: Top 66%
Biological Activity of Diterpenoids and Biflavonoids
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