Plasma Ceramides Levels in Severe COVID-19 Disease: Correlations with Survival
The synchronous trajectories of C16, C22, and C24 differ from patterns reported in chronic disease and suggest their behavior may vary with disease acuity. Their inverse trend with standard inflammatory markers resembles the behavior of negative acute-phase reactants. Further research into ceramide flux dynamics in the acute-to-subacute phase of disease is needed.
Authors
- A. Heredia Castillo
- Andrew Atkinson (ORCID: https://orcid.org/0000-0001-5834-8315)
- Linda R. Peterson (ORCID: https://orcid.org/0000-0001-8766-4552)
- Tri Pham
- M Cristina Vazquez Guillamet
Institutions
- Washington University in St. Louis (US)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1093/ofid/ofag052
- Primary Topic
- Sphingolipid Metabolism and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00