Development and validation of a clinical nomogram for predicting cumulative live birth rate in ovarian endometrioma patients undergoing ethanol sclerotherapy and in vitro fertilization/intracytoplasmic sperm injection
This study developed and validated a parsimonious nomogram model that accurately predicts the cumulative live birth rate in patients with ovarian endometriosis undergoing <i>In Vitro</i> Fertilization/Intracytoplasmic Sperm Injection after ethanol sclerotherapy. Based on four key predictors (previous live birth history, controlled ovarian hyperstimulation protocol, number of oocytes retrieved, and cyst diameter), the model demonstrates excellent and robust predictive performance. It serves as an intuitive and reliable clinical tool to support individualized counseling and shared treatment decision-making.
Authors
- J Huang
- Y. Li
- S. Liu
- Bowen Liu (ORCID: https://orcid.org/0000-0002-3546-6068)
- Shi Yuhua
- Feng Wang
- Weifen Deng
- Qian Zhou
- Chahui Zhang
Institutions
- Nanfang Hospital (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Shenzhen Zhongshan Urological Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-02-06
- DOI
- https://doi.org/10.3389/fendo.2026.1738786
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Health Promotion Foundation
- National Key Research and Development Program of China
- Basic and Applied Basic Research Foundation of Guangdong Province