Development and validation of a clinical nomogram for predicting cumulative live birth rate in ovarian endometrioma patients undergoing ethanol sclerotherapy and in vitro fertilization/intracytoplasmic sperm injection

This study developed and validated a parsimonious nomogram model that accurately predicts the cumulative live birth rate in patients with ovarian endometriosis undergoing <i>In Vitro</i> Fertilization/Intracytoplasmic Sperm Injection after ethanol sclerotherapy. Based on four key predictors (previous live birth history, controlled ovarian hyperstimulation protocol, number of oocytes retrieved, and cyst diameter), the model demonstrates excellent and robust predictive performance. It serves as an intuitive and reliable clinical tool to support individualized counseling and shared treatment decision-making.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-02-06
DOI
https://doi.org/10.3389/fendo.2026.1738786
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Development and validation of a clinical nomogram for predicting cumulative live birth rate in ovarian endometrioma patients undergoing ethanol sclerotherapy and in vitro fertilization/intracytoplasmic sperm injection

J Huang, Y. Li, S. Liu, Bowen Liu et al.
Frontiers in Endocrinology
Endometriosis Research and Treatment
article

Development and validation of a clinical nomogram for predicting cumulative live birth rate in ovarian endometrioma patients undergoing ethanol sclerotherapy and in vitro fertilization/intracytoplasmic sperm injection

J Huang, Y. Li, S. Liu, Bowen Liu, Shi Yuhua, Feng Wang, Weifen Deng, Qian Zhou, Chahui Zhang
article en

Abstract

This study developed and validated a parsimonious nomogram model that accurately predicts the cumulative live birth rate in patients with ovarian endometriosis undergoing <i>In Vitro</i> Fertilization/Intracytoplasmic Sperm Injection after ethanol sclerotherapy. Based on four key predictors (previous live birth history, controlled ovarian hyperstimulation protocol, number of oocytes retrieved, and cyst diameter), the model demonstrates excellent and robust predictive performance. It serves as an intuitive and reliable clinical tool to support individualized counseling and shared treatment decision-making.

Frontiers in EndocrinologyVol. 17
Nanfang Hospital (CN), Guangdong Academy of Medical Sciences (CN), Guangdong Provincial People's Hospital (CN), Shenzhen Zhongshan Urological Hospital (CN), Southern Medical University (CN)
China Health Promotion Foundation, National Key Research and Development Program of China, Basic and Applied Basic Research Foundation of Guangdong Province
Peace, Justice and strong institutions
Openalex Percentile: Top 67%
Endometriosis Research and Treatment
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