Optimization of α‐Synuclein and Tau Detection by Immunoblot in Enteroendocrine Cell Lines
Our results indicate that NCI-H716 cells represent an ideal EEC model for studying α-synuclein expression and phosphorylation, whereas GLUTag cells are preferable for investigating tau protein biology. This work provides a comprehensive antibody toolbox to dissect the physiological and pathological role of α-synuclein and tau in EECs.
Authors
- Giuseppe Madaro
- Thibauld Oullier
- M. Neunlist
- P Charbonneau
- Pascal Derkinderen
- Gwenola Le Dréan
Institutions
- Inserm (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- The Enteric Nervous System in Gut and Brain Disorders (FR)
- PhysioPathologie des Adaptations Nutritionnelles (FR)
- Nantes Université (FR)
Publication Details
- Journal
- Neurogastroenterology & Motility
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1111/nmo.70259
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00