Development and validation of simplified prognostic models for 14- and 30-day mortality in advanced cancer: beyond the glasgow prognostic score

GPS and mGPS are inadequate for week-level prognostication in advanced cancer, whereas simplified models integrating objective clinical and laboratory variables improve discrimination, calibration, and potential clinical utility. The eight-variable model may facilitate real-world implementation in end-of-life care.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-05
DOI
https://doi.org/10.3389/fonc.2026.1729131
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Development and validation of simplified prognostic models for 14- and 30-day mortality in advanced cancer: beyond the glasgow prognostic score

Jhen-Ling Huang, Wan-Ling Yang
Frontiers in Oncology
Sepsis Diagnosis and Treatment
article

Development and validation of simplified prognostic models for 14- and 30-day mortality in advanced cancer: beyond the glasgow prognostic score

Jhen-Ling Huang, Wan-Ling Yang
article en

Abstract

GPS and mGPS are inadequate for week-level prognostication in advanced cancer, whereas simplified models integrating objective clinical and laboratory variables improve discrimination, calibration, and potential clinical utility. The eight-variable model may facilitate real-world implementation in end-of-life care.

Frontiers in OncologyVol. 16
Taipei Veterans General Hospital (TW), Far Eastern Memorial Hospital (TW)
Peace, Justice and strong institutions
Openalex Percentile: Top 64%
Sepsis Diagnosis and Treatment
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