Environmental ciprofloxacin triggers pregnancy loss: senescence-driven miscarriage via TRIM21-mediated MFF degradation
This work was supported by the NSFC (NSFC No. 82373602 and No. 82571347), SMRF (No. B2303002), GBABRF (2023B1515120054 and 2023A1515110497), NSFC Joint Fund Key Support Project (grant no. U24A20748), the JITCBR (202407), HCGP (A2024281), SSTP (No. JCYJ20220530144403008, JCYJ20220818103607015, JCYJ20230807111401002, JCYJ20240813180400002, and JCYJ20241202152800001), CRSFFWJMF 320.6750.2022-06-47, FHRP (No. FTWS011 and FTWS2022002).
Authors
- Qingzhi Hou (ORCID: https://orcid.org/0000-0001-6475-5451)
- Yanxin Wang
- Linlin Wu (ORCID: https://orcid.org/0000-0002-7236-6787)
- Zhengzhong Wu
- Haijun Yan
- Shuaishuai Xing (幸帅帅)
- Zhihong Zhang
- Wenli Cheng
- Chenghui Huang
- Wenxin Huang (黄文欣)
- Yanbing Lin (林晏冰)
- Huidong Zhang (张慧东)
- Geng Guo
- Depeng Zhao
- Yi Sun (孙义)
Institutions
- Sun Yat-sen University (CN)
- Shanxi Medical University (CN)
- Shenzhen Maternity and Child Healthcare Hospital (CN)
- First Hospital of Shanxi Medical University (CN)
- Eighth Affiliated Hospital of Sun Yat-sen University
Publication Details
- Journal
- EBioMedicine
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1016/j.ebiom.2026.106146
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00