Quantitative proteomics and phosphoproteomics reveal glucocorticoid stimulation of TLR and Rho GTPase signaling in neutrophil-like cells
Our results not only reveal unconventional regulatory mechanisms of glucocorticoids in the human immune system but also provide valuable resources for discovering novel glucocorticoid-responsive protein targets in neutrophils.
Authors
- Michael L. Nielsen (ORCID: https://orcid.org/0000-0002-0067-9039)
- Hayoung Cho (ORCID: https://orcid.org/0000-0002-3447-6993)
- Jesper Velgaard Olsen (ORCID: https://orcid.org/0000-0002-4747-4938)
Institutions
- Novo Nordisk Foundation (DK)
Publication Details
- Journal
- Genome biology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1186/s13059-026-03985-4
- Citations
- 1
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 24.43
Funders
- Novo Nordisk Fonden