Xylosyltransferase-I in knee arthrofibrosis: Mechanistic insights and translational implications
XT-I holds promise as a synovial biomarker and potential therapeutic target in arthrofibrosis. Targeting XT-I, potentially in combination with core pathway inhibitors (e.g., Wnt/ß-catenin inhibitors), may offer a refined strategy for early diagnosis and postoperative management in TKA patients.
Authors
- Michael Jagodzinski
- Chao Lou (ORCID: https://orcid.org/0000-0002-0575-1941)
- Yong Huang
Institutions
- Medizinische Hochschule Hannover (DE)
- Sana Kliniken AG (DE)
Publication Details
- Journal
- Journal of Orthopaedics
- Published
- 2026-02-06
- DOI
- https://doi.org/10.1016/j.jor.2026.02.031
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00