A systems biology framework uncovers multi-level genetic regulation of dizziness/vertigo through eQTL–GWAS integration and single-cell analysis
This integrative analysis links gene expres-sion regulation to dizziness/vertigo across neuroimmune and metabolic systems. The findings uncover coordinated molecular pathways underlying disease susceptibility and highlight novel therapeutic targets, providing a foundation for precision treatment strate-gies.
Authors
- Hao Wang (ORCID: https://orcid.org/0000-0001-6881-9977)
- Lili Zhang (ORCID: https://orcid.org/0000-0002-4339-1502)
- Shuo Li
- Jiaqi Bai
- Dingduo Shan
Institutions
- Shenyang Pharmaceutical University (CN)
- Chinese PLA General Hospital (CN)
- Institute of Pharmacology (CZ)
Publication Details
- Journal
- International Journal of Neuroscience
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1080/00207454.2026.2627258
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00