Spatial amyloid–informed multimodal brain age as an early marker of Alzheimer’s-related vulnerability and risk stratification
An amyloid-informed multimodal BAG model captures convergent AD-related pathology, biomarker alterations, and cognitive vulnerability beyond amyloid burden alone, supporting its value for individualized risk s2tratification and prevention-focused assessment.
Authors
- Yihui Guan (ORCID: https://orcid.org/0000-0003-3001-7965)
- You-Yi Tu
- Liang Cui (ORCID: https://orcid.org/0009-0002-1648-5033)
- Min Wang
- Jie-Hui Jiang
- Fang Xie
- Zhen Zhang
- Yue-Hua Li
- Qing-Min Wang
- Qi-Hao Guo
Institutions
- Shanghai University (CN)
- Fudan University (CN)
- Shanghai Sixth People's Hospital (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- The Journal of Prevention of Alzheimer s Disease
- Published
- 2026-02-06
- DOI
- https://doi.org/10.1016/j.tjpad.2026.100501
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00