Accuracy of Fecal Immunochemical Tests for Detecting Advanced Colorectal Neoplasia at Surveillance Colonoscopy

Lowering the FIT hemoglobin cutoff markedly improved sensitivity for detecting advanced precancerous lesions in patients without previous advanced polyps. Serial testing could further enhance detection. FIT-based surveillance should be further evaluated as a potential strategy to prioritize, delay, or replace colonoscopy.

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Publication Details

Journal
Clinical and Translational Gastroenterology
Published
2026-02-06
DOI
https://doi.org/10.14309/ctg.0000000000000997
Primary Topic
Colorectal Cancer Screening and Detection
Type
article
Field-Weighted Citation Impact
0.00
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article

Accuracy of Fecal Immunochemical Tests for Detecting Advanced Colorectal Neoplasia at Surveillance Colonoscopy

Yi Xu, Jessica C. Sieren, Jeanette M. Daly, Seth D Crockett et al.
Clinical and Translational Gastroenterology
Colorectal Cancer Screening and Detection
article

Accuracy of Fecal Immunochemical Tests for Detecting Advanced Colorectal Neoplasia at Surveillance Colonoscopy

Yi Xu, Jessica C. Sieren, Jeanette M. Daly, Seth D Crockett, Gloria D Coronado, Barcey T Levy
article en

Abstract

Lowering the FIT hemoglobin cutoff markedly improved sensitivity for detecting advanced precancerous lesions in patients without previous advanced polyps. Serial testing could further enhance detection. FIT-based surveillance should be further evaluated as a potential strategy to prioritize, delay, or replace colonoscopy.

Clinical and Translational Gastroenterology
University of Iowa (US), University of Arizona (US), Oregon Health & Science University (US), Arizona Science Center (US), Portland VA Medical Center (US)
Good health and well-being
Openalex Percentile: Top 65%
Colorectal Cancer Screening and Detection
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