Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence-based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype-endotype classification and targeted therapies. Concurrently, Chinese research has achieved globally competitive milestones, including phenotype-endotype-driven mechanistic studies, biomarker discovery, and high-quality RCTs evaluating biologics, significantly advancing precision management algorithms. This 2024 update rigorously incorporates China-specific evidence from systematic literature reviews and multicenter studies. Key revisions address critical clinical challenges through structured expert consensus. Newly added evidence tiers and clinical decision pathways enhance practicality for diverse healthcare settings. By integrating domestic innovations with global standards, this guideline establishes a pragmatic framework for personalized care while prioritizing real-world applicability, ultimately aiming to standardize CRS management in China's evolving clinical landscape.

Authors

Publication Details

Journal
World Journal of Otorhinolaryngology - Head and Neck Surgery
Published
2025-08-14
DOI
https://doi.org/10.1002/wjo2.70031
Primary Topic
Sinusitis and nasal conditions
Type
article
Field-Weighted Citation Impact
0.00

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article

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery Subspecialty Group of Rhinology
World Journal of Otorhinolaryngology - Head and Neck Surgery
Sinusitis and nasal conditions
article

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery Subspecialty Group of Rhinology
article en

Abstract

Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence-based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype-endotype classification and targeted therapies. Concurrently, Chinese research has achieved globally competitive milestones, including phenotype-endotype-driven mechanistic studies, biomarker discovery, and high-quality RCTs evaluating biologics, significantly advancing precision management algorithms. This 2024 update rigorously incorporates China-specific evidence from systematic literature reviews and multicenter studies. Key revisions address critical clinical challenges through structured expert consensus. Newly added evidence tiers and clinical decision pathways enhance practicality for diverse healthcare settings. By integrating domestic innovations with global standards, this guideline establishes a pragmatic framework for personalized care while prioritizing real-world applicability, ultimately aiming to standardize CRS management in China's evolving clinical landscape.

World Journal of Otorhinolaryngology - Head and Neck SurgeryVol. 12(1)
Shandong University, Harbin Medical University, Qilu Hospital of Shandong University, Lanzhou University, Peking University First Hospital, Second Affiliated Hospital of Harbin Medical University, Sun Yat-sen University, Capital Medical University, Central South University, Fudan University, Huazhong University of Science and Technology, Jilin University, Tongji University, Zhengzhou University, Nanchang University, Xinjiang Medical University, Sichuan University, Shanghai Jiao Tong University, Nanjing Medical University, Peking University, Shanxi Medical University, General Hospital of People’s Liberation Army, Tianjin Medical University, Guizhou Medical University, Guangxi Medical University, Peking University People's Hospital, First Affiliated Hospital of Zhengzhou University, Henan Provincial People's Hospital, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Xiangya Hospital, Central South University, National Key Research and Development Program of China, Tongji Medical College, Huazhong University of Science and Technology, West China Hospital, Sichuan University, Beijing Friendship Hospital, Capital Medical University
Openalex Percentile: Top 23%
Sinusitis and nasal conditions
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