Evaluation of Andrographis paniculata in a mouse model of influenza A viral infection using oral administration and a translationally relevant dose
Based on the clinically relevant design of our mouse model, the results lay the groundwork for future preclinical research to determine optimal treatment schedule/dosage and immune mechanisms, thereby informing the design for future resilience efficacy clinical trials.
Authors
- Amar Gopal Chittiboyina (ORCID: https://orcid.org/0000-0002-7047-5373)
- Grace C. Burnett (ORCID: https://orcid.org/0009-0006-8317-5309)
- Kashif Shamim
- Jin Zhang
- John T. Bates
- Shabana I. Khan
- Nirmal D. Pugh
- Ikhlas A. Khan
- Nessma H. Ahmed
Institutions
- University of Mississippi Medical Center (US)
- University of Mississippi (US)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.3389/fphar.2026.1749384
- Primary Topic
- Andrographolide Research and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Agriculture
- Agricultural Research Service