Sporoplasm: The initial cell in microsporidia life cycle

We review and discuss recent research progress on the sporoplasm, particularly conducting in-depth comparative analyses of the biological characteristics of different microsporidia sporoplasm and gene expression patterns across various developmental stages. On this basis, we propose the main directions and research roadmap for future studies, including structural biology, host-parasite molecular interaction, and genetic engineering feasibility. These studies will contribute to elucidating the molecular mechanisms of microsporidia life cycle and pathogenesis.

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Publication Details

Journal
Journal of Advanced Research
Published
2026-02-01
DOI
https://doi.org/10.1016/j.jare.2026.01.085
Primary Topic
Parasitic Infections and Diagnostics
Type
article
Field-Weighted Citation Impact
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article

Sporoplasm: The initial cell in microsporidia life cycle

Qing Lv, Guoqing Pan, Mengxian Long, Mingyan Li et al.
Journal of Advanced Research
Parasitic Infections and Diagnostics
article

Sporoplasm: The initial cell in microsporidia life cycle

Qing Lv, Guoqing Pan, Mengxian Long, Mingyan Li, Maoping Shao
article en

Abstract

We review and discuss recent research progress on the sporoplasm, particularly conducting in-depth comparative analyses of the biological characteristics of different microsporidia sporoplasm and gene expression patterns across various developmental stages. On this basis, we propose the main directions and research roadmap for future studies, including structural biology, host-parasite molecular interaction, and genetic engineering feasibility. These studies will contribute to elucidating the molecular mechanisms of microsporidia life cycle and pathogenesis.

Journal of Advanced Research
Southwest University (CN)
Responsible consumption and production
Openalex Percentile: Top 62%
Parasitic Infections and Diagnostics
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