Causal Association Between Sleep Traits and Endometriosis: A Mendelian Randomization Study
Our study demonstrated a causal relationship between insomnia and elevated risks of endometriosis across multiple anatomical subtypes. While no significant associations were observed for other sleep traits, the robust link with insomnia highlights the potential clinical value of sleep-focused interventions in mitigating the risk of endometriosis.
Authors
- Yue Liu (ORCID: https://orcid.org/0000-0002-5625-0602)
- Li Ge (ORCID: https://orcid.org/0000-0002-5085-9628)
- Yujia Ren
- Linlin Hu
- Linlin Cui
- Peihao Liu
- Wenjing Wan
Institutions
- Shandong University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Second Hospital of Shandong University (CN)
- Shandong Mental Health Center (CN)
- Institute for Reproductive Health (US)
- Qilu Hospital of Shandong University (CN)
- Shandong Academy of Chinese Medicine (CN)
Publication Details
- Journal
- International Journal of Women s Health
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/ijwh.s565217
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shandong University
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province