Cognition in adults with bottom‐of‐sulcus dysplasia and the consequences of focal resection

In adults with BOSD, an earlier age of seizure onset is accompanied by a greater degree of cognitive comorbidity. Naming is commonly affected, particularly for those with left sided BOSDs. Executive dysfunction is common, particularly for patients with a frontal BOSD. Focal lesionectomy is associated with favourable seizure outcome and is cognitively safe with potential for improvement in processing speed.

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Publication Details

Journal
Epilepsia
Published
2026-02-05
DOI
https://doi.org/10.1002/epi.70116
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Cognition in adults with bottom‐of‐sulcus dysplasia and the consequences of focal resection

David L. Weintrob, Chris Tailby, Carmen Jiamin Zheng, MARIE F. O'SHEA et al.
Epilepsia
Epilepsy research and treatment
article

Cognition in adults with bottom‐of‐sulcus dysplasia and the consequences of focal resection

David L. Weintrob, Chris Tailby, Carmen Jiamin Zheng, MARIE F. O'SHEA, Graeme D. Jackson
article en

Abstract

In adults with BOSD, an earlier age of seizure onset is accompanied by a greater degree of cognitive comorbidity. Naming is commonly affected, particularly for those with left sided BOSDs. Executive dysfunction is common, particularly for patients with a frontal BOSD. Focal lesionectomy is associated with favourable seizure outcome and is cognitively safe with potential for improvement in processing speed.

Epilepsia
The University of Melbourne (AU), Florey Institute of Neuroscience and Mental Health (AU), Austin Health (AU)
Strong, Australian Government, State Government of Victoria, Medical Research Council, National Health and Medical Research Council
Quality Education
Openalex Percentile: Top 67%
Epilepsy research and treatment
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