Neuroprotective potential of a plant-based intervention in diabetic neuropathy: Biochemical and behavioral insights from a streptozotocin-induced rat model

The PHE derived from <i>Curcuma longa, Myristica fragrans</i>, and <i>Citrullus colocynthis</i> mitigates diabetic neuropathy through synergistic chemical-biological interactions targeting key mediators of oxidative stress and inflammation. These findings support the need for comprehensive evaluation of this formulation as a potential therapeutic candidate. This study enhances the current understanding of integrative approaches for managing chronic diabetic complications and provides further evidence supporting the therapeutic potential of plant-based compounds.

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Journal
World Journal of Diabetes
Published
2026-02-06
DOI
https://doi.org/10.4239/wjd.v17.i2.113992
Primary Topic
Curcumin's Biomedical Applications
Type
article
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article

Neuroprotective potential of a plant-based intervention in diabetic neuropathy: Biochemical and behavioral insights from a streptozotocin-induced rat model

Mahmood Ahmed, Kehkashan Parveen, SADAF ANWAR, Waseem Ahmad Siddiqui et al.
World Journal of Diabetes
Curcumin's Biomedical Applications
article

Neuroprotective potential of a plant-based intervention in diabetic neuropathy: Biochemical and behavioral insights from a streptozotocin-induced rat model

Mahmood Ahmed, Kehkashan Parveen, SADAF ANWAR, Waseem Ahmad Siddiqui, Mohd Adnan Kausar, Yusuf Saleem Khan, Ayman A Saleh, Suhel Parvez
article en

Abstract

The PHE derived from <i>Curcuma longa, Myristica fragrans</i>, and <i>Citrullus colocynthis</i> mitigates diabetic neuropathy through synergistic chemical-biological interactions targeting key mediators of oxidative stress and inflammation. These findings support the need for comprehensive evaluation of this formulation as a potential therapeutic candidate. This study enhances the current understanding of integrative approaches for managing chronic diabetic complications and provides further evidence supporting the therapeutic potential of plant-based compounds.

World Journal of DiabetesVol. 17(2)
Aligarh Muslim University (IN), Jamia Hamdard (IN), University of Ha'il (SA)
Good health and well-being
Openalex Percentile: Top 63%
Curcumin's Biomedical Applications
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Neuroprotective potential of a plant-based intervention in diabetic neuropathy: Biochemical and behavioral insights from a streptozotocin-induced rat model — Mahmood Ahmed, Kehkashan Parveen, et al. · World Journal of Diabetes (2026) | TGRS Research Map | TGRS