Neuroprotective potential of a plant-based intervention in diabetic neuropathy: Biochemical and behavioral insights from a streptozotocin-induced rat model
The PHE derived from <i>Curcuma longa, Myristica fragrans</i>, and <i>Citrullus colocynthis</i> mitigates diabetic neuropathy through synergistic chemical-biological interactions targeting key mediators of oxidative stress and inflammation. These findings support the need for comprehensive evaluation of this formulation as a potential therapeutic candidate. This study enhances the current understanding of integrative approaches for managing chronic diabetic complications and provides further evidence supporting the therapeutic potential of plant-based compounds.
Authors
- Mahmood Ahmed (ORCID: https://orcid.org/0000-0002-2285-7406)
- Kehkashan Parveen
- SADAF ANWAR
- Waseem Ahmad Siddiqui
- Mohd Adnan Kausar
- Yusuf Saleem Khan
- Ayman A Saleh
- Suhel Parvez
Institutions
- Aligarh Muslim University (IN)
- Jamia Hamdard (IN)
- University of Ha'il (SA)
Publication Details
- Journal
- World Journal of Diabetes
- Published
- 2026-02-06
- DOI
- https://doi.org/10.4239/wjd.v17.i2.113992
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00