Evaluation of the Quality and Suitability of Self‐Collected Vaginal and Urine Samples for Human Papillomavirus Testing: A Prospective Matched Study
Dry self-samples from a Copan FLOQSwab taken in clinic are likely to have sufficient DNA quality and accuracy for HPV testing compared with wet self-samples and clinician-collected samples if resuspension takes place up to 2 weeks, with storage at room temperature, and using the BD Onclarity assay. Urine samples using the Colli-pee device are likely to be less sensitive for HPV detected from clinician-collected samples.
Authors
- Belinda Nedjai (ORCID: https://orcid.org/0000-0001-8711-4577)
- Krishna A Patel
- Rhian Gabe (ORCID: https://orcid.org/0000-0002-0273-3094)
- R Manchanda
- Anna L. Parberry
- Jack Cuzick
- Laura White
- Hannah Mohy-Eldin
- Peter Sasien
- Sofia Vidali
- Kim Chu
- Michelle Saull
- Adam Brentnall
Institutions
- Queen Mary University of London (GB)
- Barts Health NHS Trust (GB)
- Royal London Hospital (GB)
Publication Details
- Journal
- BJOG An International Journal of Obstetrics & Gynaecology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1111/1471-0528.70170
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Barts Charity