Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study
Our findings offer global burden estimates of viable Mtb infection and reveal a sizable population recently infected with Mtb and at high risk of progression to disease. New diagnostic tools that can detect individuals with viable Mtb-particularly those who would benefit from TB preventive therapy-are urgently needed.
Authors
- César Ugarte‐Gil (ORCID: https://orcid.org/0000-0002-2833-9087)
- Hannah M. Rickman (ORCID: https://orcid.org/0000-0002-3502-0744)
- Alvaro Schwalb (ORCID: https://orcid.org/0000-0002-6518-9719)
- Katherine Chisholm Horton (ORCID: https://orcid.org/0000-0002-7542-4065)
- Peter J. Dodd (ORCID: https://orcid.org/0000-0001-5825-9347)
- Rein M. G. J. Houben
Institutions
- University of London (GB)
- University of Liverpool (GB)
- Universidad Peruana Cayetano Heredia (PE)
- Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MW)
- London School of Hygiene & Tropical Medicine (GB)
- The University of Texas Medical Branch at Galveston (US)
- University of Sheffield (GB)
Publication Details
- Journal
- PLoS Medicine
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1371/journal.pmed.1004920
- Citations
- 2
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 65.56
Funders
- London School of Hygiene and Tropical Medicine