Inhibition of dengue virus type 2 by hypericin mediated through viral envelope protein interaction
As per these findings, the E protein was seen to be a target of hypericin with an antiviral activity against DENV-2 at multiple stages by limiting viral adsorption and viral entry projecting a molecular basis for the candidate molecule as a possible anti-dengue agent.
Authors
- Jianfei Qiu
- Qiuqiu Xiao
- Jiahong Wu
- Meiling Tang
- Jinzhi Cheng
- Libo Liu
- Lianxin Qi
Institutions
- Guiyang Medical University (CN)
- Ministry of Education (KR)
- Guizhou Provincial People's Hospital (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2026-02-06
- DOI
- https://doi.org/10.1186/s12985-026-03087-4
- Primary Topic
- Natural Compound Pharmacology Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guizhou Medical University